منابع مشابه
Molecular epidemiology of sil locus in clinical Streptococcus pyogenes strains.
Streptococcus pyogenes (group A Streptococcus [GAS]) causes a wide variety of diseases, ranging from mild noninvasive to severe invasive infections. Mutations in regulatory components have been implicated in the switch from colonization to invasive phenotypes. The inactivation of the sil locus, composed of six genes encoding a quorum-sensing complex, gives rise to a highly invasive strain. Howe...
متن کاملFunctional Analysis of the Quorum-Sensing Streptococcal Invasion Locus (sil)
Group A streptococcus (GAS) causes a wide variety of human diseases, and at the same time, GAS can also circulate without producing symptoms, similar to its close commensal relative, group G streptococcus (GGS). We previously identified, by transposon-tagged mutagenesis, the streptococcal invasion locus (sil). sil is a quorum-sensing regulated locus which is activated by the autoinducer peptide...
متن کاملStreptococcus invasive locus (sil) in Group A Streptococcus causing non-invasive infections in Chennai, South India
Introduction Group A Streptococcus (GAS) causes diseases ranging from superficial skin & throat infections to severe lifethreatening diseases. Streptococcus invasive locus (sil) is a virulence gene responsible for pathogenesis of GAS. This study intends to detect the presence of sil gene among the non-invasive GAS and its association with toxin genes, erythromycin resistance genes, and emm types.
متن کاملThe sil Locus in Streptococcus Anginosus Group: Interspecies Competition and a Hotspot of Genetic Diversity
The Streptococcus Invasion Locus (Sil) was first described in Streptococcus pyogenes and Streptococcus pneumoniae, where it has been implicated in virulence. The two-component peptide signaling system consists of the SilA response regulator and SilB histidine kinase along with the SilCR signaling peptide and SilD/E export/processing proteins. The presence of an associated bacteriocin region sug...
متن کاملInternal eliminated sequences interrupting the Oxytricha 81 locus: allelic divergence, conservation, conversions, and possible transposon origins.
Internal eliminated sequences (IESs) often interrupt ciliate genes in the silent germline nucleus but are exactly excised and eliminated from the developing somatic nucleus from which genes are then expressed. Some long IESs are transposons, supporting the hypothesis that short IESs are ancient transposon relics. In light of that hypothesis and to explore the evolutionary history of a collectio...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/38294